P H A R M A G R A M
                  an educational memo from your Pharmacy and Therapeutics Committee

March, 2008


Topical Corticosteroids Autosubstitutions:

Based on an evaluation of the current topical corticosteroids on the Formulary, the Pharmacy and Therapeutics Committee agreed to establish a set of autosubstitutions based on potency and commonly prescribed products. Listed below are the approved formulary products and the corresponding potencies that will be used for substitution.

High Potency

Triamcinolone acetonide

Kenalog®, Aristocort®

Cream, Ointment

0.5%

Medium Potency

Triamcinolone acetonide

Kenalog®, Aristocort®

Cream, Ointment

0.1%

Low Potency

Hydrocortisone

Generic

Cream, Ointment

1%

Latex Sensitivity/Allergy Protocol Revised:

The Latex Allergy Protocol has been revised after a comprehensive review of the handling and preparation of IV drug products for administration to patients with latex allergies. The significant changes include:

Formulary Review of Contrast Media:

In a move to provide a comprehensive formulary listing of all drug products and recognizing that contrast media are approved by the FDA as drugs, the P&T Committee will be formally reviewing these agents and including them on the SFMC Formulary.

The first drug reviewed and approved to the Formulary was gadoteridol (ProHance®), which is used as a gadolinium-containing contrast agent.

Formulary Deletions and Autosubstitutions:

Drug Deletion

Reason

Autosubstitution

Cimetidine (Tagamet®

low use and lack of evidence for treating urticaria or anaphylaxis

Famotidine (Pepcid®)

Rubella, Measles, and Mumps Vaccines

Use of combination vaccines such as MMR is recommended by CDC

Measles, Mumps, Rubella (MMR®)

Procainamide sustained-release (Procanbid®)

Product no longer manufactured

No Autosubstitution. Regular-release